Developmental validation of STRmix™, expert software for the interpretation of forensic DNA profiles

Highlights • The developmental validation of STRmix™ following the 2015 SWGDAM Guidelines for the Validation of Probabilistic Genotyping Systems is described. • Performance of the software is discussed with respect to sensitivity, specificity, precision, accuracy, and reproducibility.

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Veröffentlicht in:Forensic science international : genetics 2016-07, Vol.23, p.226-239
Hauptverfasser: Bright, Jo-Anne, Taylor, Duncan, McGovern, Catherine, Cooper, Stuart, Russell, Laura, Abarno, Damien, Buckleton, John
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container_issue
container_start_page 226
container_title Forensic science international : genetics
container_volume 23
creator Bright, Jo-Anne
Taylor, Duncan
McGovern, Catherine
Cooper, Stuart
Russell, Laura
Abarno, Damien
Buckleton, John
description Highlights • The developmental validation of STRmix™ following the 2015 SWGDAM Guidelines for the Validation of Probabilistic Genotyping Systems is described. • Performance of the software is discussed with respect to sensitivity, specificity, precision, accuracy, and reproducibility.
doi_str_mv 10.1016/j.fsigen.2016.05.007
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Continuous method
DNA Fingerprinting
DNA mixtures
Genotype
Humans
Likelihood Functions
Microsatellite Repeats
Pathology
Polymerase Chain Reaction
Probabilistic genotyping
Sensitivity and Specificity
Software
STRmix
Validation
title Developmental validation of STRmix™, expert software for the interpretation of forensic DNA profiles
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