Developmental validation of STRmix™, expert software for the interpretation of forensic DNA profiles

Developmental validation of STRmix™, expert software for the interpretation of forensic DNA profiles

Highlights • The developmental validation of STRmix™ following the 2015 SWGDAM Guidelines for the Validation of Probabilistic Genotyping Systems is described. • Performance of the software is discussed with respect to sensitivity, specificity, precision, accuracy, and reproducibility.

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Veröffentlicht in:Forensic science international : genetics 2016-07, Vol.23, p.226-239
Hauptverfasser: Bright, Jo-Anne, Taylor, Duncan, McGovern, Catherine, Cooper, Stuart, Russell, Laura, Abarno, Damien, Buckleton, John
Format: Artikel
Sprache:eng
Schlagworte:
Continuous method
DNA Fingerprinting
DNA mixtures
Genotype
Humans
Likelihood Functions
Microsatellite Repeats
Pathology
Polymerase Chain Reaction
Probabilistic genotyping
Sensitivity and Specificity
Software
STRmix
Validation
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Zusammenfassung:Highlights • The developmental validation of STRmix™ following the 2015 SWGDAM Guidelines for the Validation of Probabilistic Genotyping Systems is described. • Performance of the software is discussed with respect to sensitivity, specificity, precision, accuracy, and reproducibility.
ISSN:1872-4973
1878-0326
DOI:10.1016/j.fsigen.2016.05.007