5-Aminolevulinic Acid Photodynamic Therapy combined with CO2 Laser Therapy in treatment of laryngeal papilloma: Case report

Highlights • The approach that we applied is that ALA-PDT via self-retaining laryngoscope under general anesthesia combined with CO2 Laser Therapy.This approach is proved safe and effective for clearing laryngeal papilloma. Laryngeal papilloma was fully removed from the three patients, with no recurrence during the 6-24 months of follow-up medical examination. • The therapy can be used for treating laryngeal papilloma. The major adverse effects were mild edema and exudation. No other adverse effects were observed.