Fe-Catalyzed Hydroalkylation of Olefins with para-Quinone Methides
A novel Fe-catalyzed hydroalkylation of olefins with para-quinone methides (p-QMs) for accessing phenols has been developed. In this protocol, various olefins could convert to alkyl radicals and undergo addition to para-quinone methides toward C–C bond formation and aromatization. The reaction condi...
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| Veröffentlicht in: | Organic letters 2016-06, Vol.18 (11), p.2722-2725 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A novel Fe-catalyzed hydroalkylation of olefins with para-quinone methides (p-QMs) for accessing phenols has been developed. In this protocol, various olefins could convert to alkyl radicals and undergo addition to para-quinone methides toward C–C bond formation and aromatization. The reaction conditions are mild and the substrate scopes are broad. |
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| ISSN: | 1523-7060 1523-7052 |
| DOI: | 10.1021/acs.orglett.6b01173 |