Biological Characterization of Low-Energy Ions with High-Energy Deposition on Human Cells

During space travel, astronauts are exposed to cosmic radiation that is comprised of high-energy nuclear particles. Cancer patients are also exposed to high-energy nuclear particles when treated with proton and carbon beams. Nuclear interactions from high-energy particles traversing shielding materi...

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Veröffentlicht in:	Radiation research 2014-09, Vol.182 (3), p.282-291
Hauptverfasser:	Saha, Janapriya, Wilson, Paul, Thieberger, Peter, Lowenstein, Derek, Wang, Minli, Cucinotta, Francis A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological effects Boron Carbon Cell cycle Cell Line Cellular Cosmic Radiation Cosmic rays Damage DNA Breaks, Double-Stranded DNA Damage DNA Repair Energy Epithelial cells Exposure G2 Phase - radiation effects Histones - analysis Homologous Recombination Humans Ion irradiation Ions Irradiation Linear Energy Transfer Low energy Nuclear particles Particle beams Particle energy Particle tracks Radiation damage REGULAR ARTICLE REGULAR ARTICLES Space life sciences
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Zusammenfassung:	During space travel, astronauts are exposed to cosmic radiation that is comprised of high-energy nuclear particles. Cancer patients are also exposed to high-energy nuclear particles when treated with proton and carbon beams. Nuclear interactions from high-energy particles traversing shielding materials and tissue produce low-energy (
ISSN:	0033-7587 1938-5404
DOI:	10.1667/RR13747.1