RTV silicone rubber surface modification for cell biocompatibility by negative-ion implantation

•The radiation effect has a greater influence than doping effect on the hydrophilicity of RTV SR.•The implanted ions result in a new surface atomic bonding state and morphology.•Generating hydrophilic functional groups is a reason for the improved cell biocompatibility.•The micro roughness makes the...

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Veröffentlicht in:Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms Beam interactions with materials and atoms, 2016-03, Vol.370, p.73-78
Hauptverfasser: Zheng, Chenlong, Wang, Guangfu, Chu, Yingjie, Xu, Ya, Qiu, Menglin, Xu, Mi
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Sprache:eng
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Zusammenfassung:•The radiation effect has a greater influence than doping effect on the hydrophilicity of RTV SR.•The implanted ions result in a new surface atomic bonding state and morphology.•Generating hydrophilic functional groups is a reason for the improved cell biocompatibility.•The micro roughness makes the hydrophilicity should be reduced due to the lotus effect.•Cell culture demonstrates that negative-ion implantation can improve biocompatibility. A negative cluster ion implantation system was built on the injector of a GIC4117 tandem accelerator. Next, the system was used to study the surface modification of room temperature vulcanization silicone rubber (RTV SR) for cell biocompatibility. The water contact angle was observed to decrease from 117.6° to 99.3° as the C1− implantation dose was increased to 1×1016ions/cm2, and the effects of C1−, C2− and O1− implantation result in only small differences in the water contact angle at 3×1015ions/cm2. These findings indicate that the hydrophilicity of RTV SR improves as the dose is increased and that the radiation effect has a greater influence than the doping effect on the hydrophilicity. There are two factors influence hydrophilicity of RTV: (1) based on the XPS and ATR-FTIR results, it can be inferred that ion implantation breaks the hydrophobic functional groups (SiCH3, SiOSi, CH) of RTV SR and generates hydrophilic functional groups (COOH, OH, Si(O)x (x=3,4)). (2) SEM reveals that the implanted surface of RTV SR appears the micro roughness such as cracks and wrinkles. The hydrophilicity should be reduced due to the lotus effect (Zhou Rui et al., 2009). These two factors cancel each other out and make the C-implantation sample becomes more hydrophilic in general terms. Finally, cell culture demonstrates that negative ion-implantation is an effective method to improve the cell biocompatibility of RTV SR.
ISSN:0168-583X
1872-9584
DOI:10.1016/j.nimb.2016.01.014