Functionalization of Aglycones on Sialoside Derivatives to Generate Precursors for Biological Applications

Sialic acid-containing glycans play numerous roles in various biological events. Fluorescent labeling and functional group transformation into versatile moieties are performed on synthesized galactose, sialyl galactose, and sialyl lactose derivatives to investigate carbohydrate-mediated biological functions. In this study, precursors for fluorescent labeling and viable substrates for investigations regarding carbohydrate-mediated biological process were developed. Specifically, allyl galactosides and allyl sialosides were functionalized to produce functional precursors for biological applications.