Follicle-stimulating hormone is associated with non-alcoholic fatty liver disease in Chinese women over 55 years old

Background and Aim Obesity and diabetes are related to non‐alcoholic fatty liver disease (NAFLD). A reduction in follicle‐stimulating hormone (FSH) is associated with obesity and diabetes in postmenopausal women. Thus, we aim to investigate whether FSH is associated with NAFLD in women over 55 who w...

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Veröffentlicht in:Journal of gastroenterology and hepatology 2016-06, Vol.31 (6), p.1196-1202
Hauptverfasser: Wang, Ningjian, Li, Qin, Han, Bing, Chen, Yi, Zhu, Chunfang, Chen, Yingchao, Xia, Fangzhen, Lu, Meng, Meng, Ying, Guo, Yuyu, Ye, Lin, Sui, Chunhua, Kuang, Lin, Lin, Dongping, Lu, Yingli
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Sprache:eng
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Zusammenfassung:Background and Aim Obesity and diabetes are related to non‐alcoholic fatty liver disease (NAFLD). A reduction in follicle‐stimulating hormone (FSH) is associated with obesity and diabetes in postmenopausal women. Thus, we aim to investigate whether FSH is associated with NAFLD in women over 55 who were postmenopausal with a high probability. Methods Our data were obtained from the 2014 Survey on Prevalence in East China for Metabolic Diseases and Risk Factors. A total of 1635 women at the age of 55–89 years were selected. The degrees of fatty liver were categorized into mild and moderate‐severe hepatic steatosis groups by ultrasonography. FSH and other sex hormones were measured by chemiluminescence. Results A total of 366 (22.4%) and 417 (25.5%) women had mild and moderate‐severe hepatic steatosis, respectively. FSH was negatively correlated with waist circumference, homeostasis model assessment of insulin resistance (HOMA‐IR), and other metabolic factors (all P 
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.13271