Is ischemia modified albumin a disease activity marker for inflammatory bowel diseases?

Background and Aim: We aimed to identify ischemia‐modified albumin (IMA) levels in inflammatory bowel disease (IBD) and IBD subgroups, and to examine its relation with disease activity index. Methods: Sixty‐eight patients with IBD (35 ulcerative colitis [UC] and 33 crohn disease [CD]) and 65 healthy...

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Veröffentlicht in:Journal of gastroenterology and hepatology 2016-06, Vol.31 (6), p.1120-1125
Hauptverfasser: Kaplan, Mustafa, Yuksel, Mahmut, Ates, Ihsan, Kilic, Zeki Mesut Yalın, Kilic, Hasan, Kuzu, Ufuk Barıs, Kayacetin, Ertugrul
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Sprache:eng
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Zusammenfassung:Background and Aim: We aimed to identify ischemia‐modified albumin (IMA) levels in inflammatory bowel disease (IBD) and IBD subgroups, and to examine its relation with disease activity index. Methods: Sixty‐eight patients with IBD (35 ulcerative colitis [UC] and 33 crohn disease [CD]) and 65 healthy volunteers were included in the study. Rachmilewitz scoring system (endoscopic activity index [EAI]) was used to determine UC activity, and as for CD activity, CD activity index (CDAI) scoring was used. IMA measurement was performed with ELISA kit. Results: Ischemia‐modified albumin levels in IBD, UC, and CD groups were comparably higher than the control group (37.7 ng/mL vs 42.4 ng/mL vs 36.4 ng/mL vs 21.8 ng/mL, respectively; P 
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.13254