Is ischemia modified albumin a disease activity marker for inflammatory bowel diseases?
Background and Aim: We aimed to identify ischemia‐modified albumin (IMA) levels in inflammatory bowel disease (IBD) and IBD subgroups, and to examine its relation with disease activity index. Methods: Sixty‐eight patients with IBD (35 ulcerative colitis [UC] and 33 crohn disease [CD]) and 65 healthy...
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Veröffentlicht in: | Journal of gastroenterology and hepatology 2016-06, Vol.31 (6), p.1120-1125 |
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Sprache: | eng |
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Zusammenfassung: | Background and Aim:
We aimed to identify ischemia‐modified albumin (IMA) levels in inflammatory bowel disease (IBD) and IBD subgroups, and to examine its relation with disease activity index.
Methods:
Sixty‐eight patients with IBD (35 ulcerative colitis [UC] and 33 crohn disease [CD]) and 65 healthy volunteers were included in the study. Rachmilewitz scoring system (endoscopic activity index [EAI]) was used to determine UC activity, and as for CD activity, CD activity index (CDAI) scoring was used. IMA measurement was performed with ELISA kit.
Results:
Ischemia‐modified albumin levels in IBD, UC, and CD groups were comparably higher than the control group (37.7 ng/mL vs 42.4 ng/mL vs 36.4 ng/mL vs 21.8 ng/mL, respectively; P |
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ISSN: | 0815-9319 1440-1746 |
DOI: | 10.1111/jgh.13254 |