Clinical Practice Patterns in Chemotherapeutic Treatment Regimens for Metastatic Colorectal Cancer
Micro-Abstract Patients with metastatic colorectal cancer are now being exposed to an increasing number of therapeutic agents. The present observational retrospective study reports the clinical practice patterns and characterizes how these agents were used and why they were discontinued in the longi...
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| Veröffentlicht in: | Clinical colorectal cancer 2016-06, Vol.15 (2), p.135-140 |
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| container_title | Clinical colorectal cancer |
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| creator | McLean, James Rho, Young Soo Kuruba, Gayathri Mamo, Aline Gilabert, Marine Kavan, Tomas Panasci, Lawrence Melnychuk, David Batist, Gerald Kavan, Petr |
| description | Micro-Abstract Patients with metastatic colorectal cancer are now being exposed to an increasing number of therapeutic agents. The present observational retrospective study reports the clinical practice patterns and characterizes how these agents were used and why they were discontinued in the longitudinal course of patient treatment. FOLFOX (5-fluorouracil, leucovorin, oxaliplatin), FOLFIRI (irinotecan, 5-fluorouracil, leucovorin), and bevacizumab were most frequently used. Most patients discontinued treatment because of disease progression. |
| doi_str_mv | 10.1016/j.clcc.2015.10.003 |
| format | Article |
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The present observational retrospective study reports the clinical practice patterns and characterizes how these agents were used and why they were discontinued in the longitudinal course of patient treatment. FOLFOX (5-fluorouracil, leucovorin, oxaliplatin), FOLFIRI (irinotecan, 5-fluorouracil, leucovorin), and bevacizumab were most frequently used. Most patients discontinued treatment because of disease progression.</description><identifier>ISSN: 1533-0028</identifier><identifier>EISSN: 1938-0674</identifier><identifier>DOI: 10.1016/j.clcc.2015.10.003</identifier><identifier>PMID: 26553578</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adenocarcinoma - drug therapy ; Adult ; Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Attrition ; Biologic ; Colorectal Neoplasms - drug therapy ; Discontinuation of therapy ; Disease Progression ; Female ; Gastroenterology and Hepatology ; Hematology, Oncology and Palliative Medicine ; Humans ; Longitudinal ; Male ; Middle Aged ; Neoplasm Metastasis ; Practice Patterns, Physicians' - statistics & numerical data ; Real world ; Retrospective Studies ; Salvage Therapy - utilization ; Young Adult</subject><ispartof>Clinical colorectal cancer, 2016-06, Vol.15 (2), p.135-140</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. 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| ispartof | Clinical colorectal cancer, 2016-06, Vol.15 (2), p.135-140 |
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| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adenocarcinoma - drug therapy Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - therapeutic use Attrition Biologic Colorectal Neoplasms - drug therapy Discontinuation of therapy Disease Progression Female Gastroenterology and Hepatology Hematology, Oncology and Palliative Medicine Humans Longitudinal Male Middle Aged Neoplasm Metastasis Practice Patterns, Physicians' - statistics & numerical data Real world Retrospective Studies Salvage Therapy - utilization Young Adult |
| title | Clinical Practice Patterns in Chemotherapeutic Treatment Regimens for Metastatic Colorectal Cancer |
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