Clinical Practice Patterns in Chemotherapeutic Treatment Regimens for Metastatic Colorectal Cancer

Micro-Abstract Patients with metastatic colorectal cancer are now being exposed to an increasing number of therapeutic agents. The present observational retrospective study reports the clinical practice patterns and characterizes how these agents were used and why they were discontinued in the longi...

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Veröffentlicht in:	Clinical colorectal cancer 2016-06, Vol.15 (2), p.135-140
Hauptverfasser:	McLean, James, Rho, Young Soo, Kuruba, Gayathri, Mamo, Aline, Gilabert, Marine, Kavan, Tomas, Panasci, Lawrence, Melnychuk, David, Batist, Gerald, Kavan, Petr
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - therapeutic use Attrition Biologic Colorectal Neoplasms - drug therapy Discontinuation of therapy Disease Progression Female Gastroenterology and Hepatology Hematology, Oncology and Palliative Medicine Humans Longitudinal Male Middle Aged Neoplasm Metastasis Practice Patterns, Physicians' - statistics & numerical data Real world Retrospective Studies Salvage Therapy - utilization Young Adult
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Zusammenfassung:	Micro-Abstract Patients with metastatic colorectal cancer are now being exposed to an increasing number of therapeutic agents. The present observational retrospective study reports the clinical practice patterns and characterizes how these agents were used and why they were discontinued in the longitudinal course of patient treatment. FOLFOX (5-fluorouracil, leucovorin, oxaliplatin), FOLFIRI (irinotecan, 5-fluorouracil, leucovorin), and bevacizumab were most frequently used. Most patients discontinued treatment because of disease progression.
ISSN:	1533-0028 1938-0674
DOI:	10.1016/j.clcc.2015.10.003