The relationship between beta-catenin and apoptosis: A cytological and immunocytochemical examination

Highlights • The relationship between the activity of the Wnt/β-catenin signaling pathway and apoptosis has not been fully elucidated. • Immunocytochemical expression of β-catenin, active caspase 3, 8, and 9 were investigated in cervicovaginal smears. • The activity of the Wnt/β-catenin signaling pa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Tissue & cell 2016-06, Vol.48 (3), p.160-167
Hauptverfasser:	Donmez, Hanife Guler, Demirezen, Sayeste, Beksac, Mehmet Sinan
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Apoptosis Apoptosis - genetics beta Catenin - biosynthesis beta Catenin - genetics Beta-catenin Caspase 3 Caspase 3 - metabolism Caspase 8 Caspase 9 Epithelial Cells - metabolism Female Gene Expression Regulation Humans Receptors, Death Domain - biosynthesis Receptors, Death Domain - isolation & purification Vaginal Smears - methods Wnt Signaling Pathway Wnt/beta-catenin signaling pathway
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • The relationship between the activity of the Wnt/β-catenin signaling pathway and apoptosis has not been fully elucidated. • Immunocytochemical expression of β-catenin, active caspase 3, 8, and 9 were investigated in cervicovaginal smears. • The activity of the Wnt/β-catenin signaling pathway was highly related to death-receptor mediated apoptosis. • The activity of the Wnt/β-catenin signaling pathway in non-apoptotic cells may be associated with the tissue homeostasis.
ISSN:	0040-8166 1532-3072
DOI:	10.1016/j.tice.2016.04.001