Intrinsic protective mechanisms of the neuron-glia network against glioma invasion

Intrinsic protective mechanisms of the neuron-glia network against glioma invasion

Highlights • The normal neuron-glia network of the brain has many molecules that inhibit cellular invasion, including that of glioma. • Radiation therapy may injure the innate inhibitory mechanisms favoring tumor invasion. • To understand the interaction between glioma cells and the surrounding neur...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of clinical neuroscience 2016-04, Vol.26, p.19-25
Hauptverfasser: Iwadate, Yasuo, Fukuda, Kazumasa, Matsutani, Tomoo, Saeki, Naokatsu
Format: Artikel
Sprache:eng
Schlagworte:
Astrocyte
Brain Neoplasms - pathology
Glioma - pathology
Humans
Myelin
Myelin Sheath - pathology
Neoplasm Invasiveness - pathology
Neuroglia - pathology
Neurology
Neuron-glia network
Neurons - pathology
Oligodendrocyte
Proteoglycan
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Highlights • The normal neuron-glia network of the brain has many molecules that inhibit cellular invasion, including that of glioma. • Radiation therapy may injure the innate inhibitory mechanisms favoring tumor invasion. • To understand the interaction between glioma cells and the surrounding neuron-glia network is crucial for developing new therapies.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2015.07.024