Polymers in drug delivery

Advances in polymer science have led to the development of several novel drug-delivery sytems. A proper consideration of surface and bulk properties can aid in the designing of polymers for various drug-delivery applications. Biodegradable polymers find widespread use in drug delivery as they can be...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Current Opinion in Chemical Biology 2001-08, Vol.5 (4), p.447-451
Hauptverfasser: Pillai, Omathanu, Panchagnula, Ramesh
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 451
container_issue 4
container_start_page 447
container_title Current Opinion in Chemical Biology
container_volume 5
creator Pillai, Omathanu
Panchagnula, Ramesh
description Advances in polymer science have led to the development of several novel drug-delivery sytems. A proper consideration of surface and bulk properties can aid in the designing of polymers for various drug-delivery applications. Biodegradable polymers find widespread use in drug delivery as they can be degraded to non-toxic monomers inside the body. Novel supramolecular structures based on polyethylene oxide copolymers and dendrimers are being intensively researched for delivery of genes and macromolecules. Hydrogels that can respond to a variety of physical, chemical and biological stimuli hold enormous potential for design of closed-loop drug-delivery systems. Design and synthesis of novel combinations of polymers will expand the scope of new drug-delivery systems in the future.
doi_str_mv 10.1016/S1367-5931(00)00227-1
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_17901155</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1367593100002271</els_id><sourcerecordid>17901155</sourcerecordid><originalsourceid>FETCH-LOGICAL-c444t-ee24d59053071557a62f0ff2a4e3d7ad6ee864ff75f4ebc84086baab775adb763</originalsourceid><addsrcrecordid>eNqFkEtLAzEUhYMotlZ_gAulK9HF6E0mj5mVSPEFBQV1HTLJjURmOjXpFPrvnT7Epat7F985h3MIOaNwTYHKmzeaS5WJMqeXAFcAjKmM7pEhLVSZAQe23_-_yIAcpfQFAJIV4pAMKOUKJJRDcvra1qsGYxqH2djF7nPssA5LjKtjcuBNnfBkd0fk4-H-ffKUTV8enyd308xyzhcZIuNOlCByUFQIZSTz4D0zHHOnjJOIheTeK-E5VrbgUMjKmEopYVylZD4iF1vfeWy_O0wL3YRksa7NDNsuaapKoL1zD4otaGObUkSv5zE0Jq40Bb3eRG820evCGkBvNtG0153vArqqQfen2o3QA7dbAPuay4BRJxtwZtGFiHahXRv-ifgBhQFvRw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>17901155</pqid></control><display><type>article</type><title>Polymers in drug delivery</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Pillai, Omathanu ; Panchagnula, Ramesh</creator><creatorcontrib>Pillai, Omathanu ; Panchagnula, Ramesh</creatorcontrib><description>Advances in polymer science have led to the development of several novel drug-delivery sytems. A proper consideration of surface and bulk properties can aid in the designing of polymers for various drug-delivery applications. Biodegradable polymers find widespread use in drug delivery as they can be degraded to non-toxic monomers inside the body. Novel supramolecular structures based on polyethylene oxide copolymers and dendrimers are being intensively researched for delivery of genes and macromolecules. Hydrogels that can respond to a variety of physical, chemical and biological stimuli hold enormous potential for design of closed-loop drug-delivery systems. Design and synthesis of novel combinations of polymers will expand the scope of new drug-delivery systems in the future.</description><identifier>ISSN: 1367-5931</identifier><identifier>EISSN: 1879-0402</identifier><identifier>DOI: 10.1016/S1367-5931(00)00227-1</identifier><identifier>PMID: 11470609</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Biodegradation, Environmental ; bulk properties ; dendrimers ; Drug Carriers ; drug delivery ; Drug Delivery Systems ; hydrogels ; PGA ; polyethylene oxide ; Polymers ; surface properties</subject><ispartof>Current Opinion in Chemical Biology, 2001-08, Vol.5 (4), p.447-451</ispartof><rights>2001 Elsevier Science Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-ee24d59053071557a62f0ff2a4e3d7ad6ee864ff75f4ebc84086baab775adb763</citedby><cites>FETCH-LOGICAL-c444t-ee24d59053071557a62f0ff2a4e3d7ad6ee864ff75f4ebc84086baab775adb763</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1367593100002271$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>313,314,776,780,788,3537,27899,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11470609$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pillai, Omathanu</creatorcontrib><creatorcontrib>Panchagnula, Ramesh</creatorcontrib><title>Polymers in drug delivery</title><title>Current Opinion in Chemical Biology</title><addtitle>Curr Opin Chem Biol</addtitle><description>Advances in polymer science have led to the development of several novel drug-delivery sytems. A proper consideration of surface and bulk properties can aid in the designing of polymers for various drug-delivery applications. Biodegradable polymers find widespread use in drug delivery as they can be degraded to non-toxic monomers inside the body. Novel supramolecular structures based on polyethylene oxide copolymers and dendrimers are being intensively researched for delivery of genes and macromolecules. Hydrogels that can respond to a variety of physical, chemical and biological stimuli hold enormous potential for design of closed-loop drug-delivery systems. Design and synthesis of novel combinations of polymers will expand the scope of new drug-delivery systems in the future.</description><subject>Biodegradation, Environmental</subject><subject>bulk properties</subject><subject>dendrimers</subject><subject>Drug Carriers</subject><subject>drug delivery</subject><subject>Drug Delivery Systems</subject><subject>hydrogels</subject><subject>PGA</subject><subject>polyethylene oxide</subject><subject>Polymers</subject><subject>surface properties</subject><issn>1367-5931</issn><issn>1879-0402</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMotlZ_gAulK9HF6E0mj5mVSPEFBQV1HTLJjURmOjXpFPrvnT7Epat7F985h3MIOaNwTYHKmzeaS5WJMqeXAFcAjKmM7pEhLVSZAQe23_-_yIAcpfQFAJIV4pAMKOUKJJRDcvra1qsGYxqH2djF7nPssA5LjKtjcuBNnfBkd0fk4-H-ffKUTV8enyd308xyzhcZIuNOlCByUFQIZSTz4D0zHHOnjJOIheTeK-E5VrbgUMjKmEopYVylZD4iF1vfeWy_O0wL3YRksa7NDNsuaapKoL1zD4otaGObUkSv5zE0Jq40Bb3eRG820evCGkBvNtG0153vArqqQfen2o3QA7dbAPuay4BRJxtwZtGFiHahXRv-ifgBhQFvRw</recordid><startdate>20010801</startdate><enddate>20010801</enddate><creator>Pillai, Omathanu</creator><creator>Panchagnula, Ramesh</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20010801</creationdate><title>Polymers in drug delivery</title><author>Pillai, Omathanu ; Panchagnula, Ramesh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-ee24d59053071557a62f0ff2a4e3d7ad6ee864ff75f4ebc84086baab775adb763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Biodegradation, Environmental</topic><topic>bulk properties</topic><topic>dendrimers</topic><topic>Drug Carriers</topic><topic>drug delivery</topic><topic>Drug Delivery Systems</topic><topic>hydrogels</topic><topic>PGA</topic><topic>polyethylene oxide</topic><topic>Polymers</topic><topic>surface properties</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pillai, Omathanu</creatorcontrib><creatorcontrib>Panchagnula, Ramesh</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Current Opinion in Chemical Biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pillai, Omathanu</au><au>Panchagnula, Ramesh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Polymers in drug delivery</atitle><jtitle>Current Opinion in Chemical Biology</jtitle><addtitle>Curr Opin Chem Biol</addtitle><date>2001-08-01</date><risdate>2001</risdate><volume>5</volume><issue>4</issue><spage>447</spage><epage>451</epage><pages>447-451</pages><issn>1367-5931</issn><eissn>1879-0402</eissn><abstract>Advances in polymer science have led to the development of several novel drug-delivery sytems. A proper consideration of surface and bulk properties can aid in the designing of polymers for various drug-delivery applications. Biodegradable polymers find widespread use in drug delivery as they can be degraded to non-toxic monomers inside the body. Novel supramolecular structures based on polyethylene oxide copolymers and dendrimers are being intensively researched for delivery of genes and macromolecules. Hydrogels that can respond to a variety of physical, chemical and biological stimuli hold enormous potential for design of closed-loop drug-delivery systems. Design and synthesis of novel combinations of polymers will expand the scope of new drug-delivery systems in the future.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>11470609</pmid><doi>10.1016/S1367-5931(00)00227-1</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1367-5931
ispartof Current Opinion in Chemical Biology, 2001-08, Vol.5 (4), p.447-451
issn 1367-5931
1879-0402
language eng
recordid cdi_proquest_miscellaneous_17901155
source MEDLINE; Elsevier ScienceDirect Journals
subjects Biodegradation, Environmental
bulk properties
dendrimers
Drug Carriers
drug delivery
Drug Delivery Systems
hydrogels
PGA
polyethylene oxide
Polymers
surface properties
title Polymers in drug delivery
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T22%3A54%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Polymers%20in%20drug%20delivery&rft.jtitle=Current%20Opinion%20in%20Chemical%20Biology&rft.au=Pillai,%20Omathanu&rft.date=2001-08-01&rft.volume=5&rft.issue=4&rft.spage=447&rft.epage=451&rft.pages=447-451&rft.issn=1367-5931&rft.eissn=1879-0402&rft_id=info:doi/10.1016/S1367-5931(00)00227-1&rft_dat=%3Cproquest_cross%3E17901155%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=17901155&rft_id=info:pmid/11470609&rft_els_id=S1367593100002271&rfr_iscdi=true