Polymers in drug delivery
Advances in polymer science have led to the development of several novel drug-delivery sytems. A proper consideration of surface and bulk properties can aid in the designing of polymers for various drug-delivery applications. Biodegradable polymers find widespread use in drug delivery as they can be...
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Veröffentlicht in: | Current Opinion in Chemical Biology 2001-08, Vol.5 (4), p.447-451 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Advances in polymer science have led to the development of several novel drug-delivery sytems. A proper consideration of surface and bulk properties can aid in the designing of polymers for various drug-delivery applications. Biodegradable polymers find widespread use in drug delivery as they can be degraded to non-toxic monomers inside the body. Novel supramolecular structures based on polyethylene oxide copolymers and dendrimers are being intensively researched for delivery of genes and macromolecules. Hydrogels that can respond to a variety of physical, chemical and biological stimuli hold enormous potential for design of closed-loop drug-delivery systems. Design and synthesis of novel combinations of polymers will expand the scope of new drug-delivery systems in the future. |
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ISSN: | 1367-5931 1879-0402 |
DOI: | 10.1016/S1367-5931(00)00227-1 |