Differential effects of somatostatin on exploratory behavior after unilateral injections into rat neostriatum
The effects of somatostatin (SRIF) microinjected unilaterally (left or right) at a dose of 10, 50, and 100 ng into the neostriatum of male Wistar rats on exploratory behavior were studied. Unilateral injections of SRIF suppressed dose-related the exploratory activity as decreased the number of horiz...
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| Veröffentlicht in: | Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2004, Vol.25 (1), p.123-128 |
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| container_title | Peptides (New York, N.Y. : 1980) |
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| creator | Tashev, Roman Belcheva, Stiliana Belcheva, Iren |
| description | The effects of somatostatin (SRIF) microinjected unilaterally (left or right) at a dose of 10, 50, and 100
ng into the neostriatum of male Wistar rats on exploratory behavior were studied. Unilateral injections of SRIF suppressed dose-related the exploratory activity as decreased the number of horizontal and vertical movements compared to the respective controls. The effect was more pronounced when SRIF was microinjected into the right neostriatum as compared to the left neostriatum. These findings suggest some asymmetric effects of SRIF, depending on the dose and the microinjected hemisphere. |
| doi_str_mv | 10.1016/j.peptides.2003.11.004 |
| format | Article |
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| ispartof | Peptides (New York, N.Y. : 1980), 2004, Vol.25 (1), p.123-128 |
| issn | 0196-9781 1873-5169 |
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| source | ScienceDirect Journals (5 years ago - present) |
| subjects | Asymmetry Biological and medical sciences Exploratory behavior Fundamental and applied biological sciences. Psychology Neostriatum Rat Somatostatin Vertebrates: endocrinology |
| title | Differential effects of somatostatin on exploratory behavior after unilateral injections into rat neostriatum |
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