Randomized clinical trial comparing self-gripping mesh with a standard polypropylene mesh for open inguinal hernia repair

Background The introduction of mesh for open inguinal hernia repair has reduced the rate of recurrence, allowing research to focus on prevention of postoperative pain. In an effort to reduce chronic pain, a semiresorbable, lighter and self‐gripping mesh was developed. Methods A double‐blind randomized clinical trial was conducted comparing the self‐gripping mesh with a standard polypropylene mesh repair. Patients over 18 years of age undergoing open primary hernia repair were included. Pain was measured on a six‐point verbal rating scale (VRS) and a 150‐mm visual analogue scale (VAS). Postoperative pain reduction from baseline pain (ΔVAS), complications and return to work/hobbies were studied. Data were collected at baseline, 3 weeks, 3 months and 1 year after surgery (primary outcome). Results A total of 363 patients were analysed. Median age was 59 (range 19–88) years. Baseline VRS and VAS scores were similar for the two groups. There was no difference in VRS scores at 1‐year follow‐up. Duration of surgery was significantly shorter with the self‐gripping mesh (mean 40 min versus 49 min for standard mesh repair; P