Relationship Between Anticoagulation Intensity and Thrombotic or Bleeding Outcomes Among Outpatients With Continuous-Flow Left Ventricular Assist Devices

We evaluated thrombotic and bleeding outcomes in patients with continuous-flow left ventricular assist devices (CF-LVADs), stratified by anticoagulation intensity. Previous studies of outpatients with CF-LVADs have suggested that target international normalized ratio (INR) values

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Bibliographische Detailangaben
Veröffentlicht in:	Circulation. Heart failure 2016-05, Vol.9 (5)
Hauptverfasser:	Nassif, Michael E, LaRue, Shane J, Raymer, David S, Novak, Eric, Vader, Justin M, Ewald, Gregory A, Gage, Brian F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anticoagulants - administration & dosage Anticoagulants - adverse effects Blood Coagulation - drug effects Drug Monitoring - methods Female Gastrointestinal Hemorrhage - chemically induced Heart Failure - diagnosis Heart Failure - mortality Heart Failure - physiopathology Heart Failure - therapy Heart-Assist Devices - adverse effects Humans International Normalized Ratio Intracranial Hemorrhages - chemically induced Intracranial Thrombosis - blood Intracranial Thrombosis - etiology Intracranial Thrombosis - mortality Intracranial Thrombosis - prevention & control Male Middle Aged Missouri Multivariate Analysis Outpatients Predictive Value of Tests Proportional Hazards Models Prosthesis Design Retrospective Studies Risk Factors Stroke - blood Stroke - etiology Stroke - mortality Stroke - prevention & control Time Factors Treatment Outcome Ventricular Function, Left Young Adult
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Beschreibung
Zusammenfassung:	We evaluated thrombotic and bleeding outcomes in patients with continuous-flow left ventricular assist devices (CF-LVADs), stratified by anticoagulation intensity. Previous studies of outpatients with CF-LVADs have suggested that target international normalized ratio (INR) values
ISSN:	1941-3289 1941-3297
DOI:	10.1161/CIRCHEARTFAILURE.115.002680