Pregnancy following Mustard or Senning correction of transposition of the great arteries: a retrospective study

Objective To determine pregnancy outcome in women with atrial switch repair for transposition of the great arteries (TGA) and to compare follow up with a control group of childless women with the same repair. Design Retrospective cohort study. Setting Tertiary care medical centre. Population About 2...

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Veröffentlicht in:BJOG : an international journal of obstetrics and gynaecology 2016-04, Vol.123 (5), p.807-813
Hauptverfasser: Cataldo, S, Doohan, M, Rice, K, Trinder, J, Stuart, AG, Curtis, SL
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Sprache:eng
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Zusammenfassung:Objective To determine pregnancy outcome in women with atrial switch repair for transposition of the great arteries (TGA) and to compare follow up with a control group of childless women with the same repair. Design Retrospective cohort study. Setting Tertiary care medical centre. Population About 21 patients compared with 15 controls. Methods Review of records from joint cardiac‐obstetric clinic 1993–2013. Main outcome measures Occurrence of cardiovascular events: maternal death, heart failure, arrhythmia, thromboembolic events, worsening systemic ventricular function, worsening tricuspid valve regurgitation and newly detected baffle problems. Results There were 34 pregnancies in 21 women. Mean follow up was 100 months. No deaths or recurrence occurred. Events (few arrhythmias, thromboembolic events and baffle issues) were common in both groups: 13 (62%) patients and eight (53%) controls (P = 0.736). Worsening of ventricular function was similar in both groups: six (29%) patients and four (27%) controls (P = 0.899). Worsening tricuspid regurgitation was more common in patients [11 (52%)] than controls (0)] (P 
ISSN:1470-0328
1471-0528
DOI:10.1111/1471-0528.13508