Apparent Diffusion Coefficient (ADC) Change on Repeated Diffusion-Weighted Magnetic Resonance Imaging during Radiochemotherapy for Non-Small Cell Lung Cancer: A Pilot Study

Highlights • The potential role of DW-MRI for response assessment of radiotherapy of lung cancer. • ADC values depend on the definition of the region of interest. • ADC values increase during radiochemotherapy. • ADC value increase appears to be independent from tumor volume regression.

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Bibliographische Detailangaben
Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2016-06, Vol.96, p.113-119
Hauptverfasser:	Weiss, Elisabeth, Ford, John C, Olsen, Kathryn M, Karki, Kishor, Saraiya, Siddharth, Groves, Robert, Hugo, Geoffrey D
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Carcinoma, Non-Small-Cell Lung - diagnostic imaging Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Non-Small-Cell Lung - therapy Chemoradiotherapy Diffusion Magnetic Resonance Imaging - methods Diffusion-weighted MRI Female Hematology, Oncology and Palliative Medicine Humans Lung Neoplasms - diagnostic imaging Lung Neoplasms - pathology Lung Neoplasms - therapy Male Middle Aged Neoplasm Staging Non small cell lung cancer Pilot Projects Pulmonary/Respiratory Radiotherapy Reproducibility of Results Response assessment Tumor Burden - drug effects
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Beschreibung
Zusammenfassung:	Highlights • The potential role of DW-MRI for response assessment of radiotherapy of lung cancer. • ADC values depend on the definition of the region of interest. • ADC values increase during radiochemotherapy. • ADC value increase appears to be independent from tumor volume regression.
ISSN:	0169-5002 1872-8332
DOI:	10.1016/j.lungcan.2016.04.001