Promising biological monitoring for occupational 1,2-Dichloropropane exposure by urinalysis for unmetabolized solvent

[Abstract]: [Objectives]: The aim of this study was to examine the applicability of urinalysis for unmetabolized solvent to biomonitor 1,2-dichloropropane (1,2-DCP) exposure. [Methods]: Thirty three male printers exposed to 1,2-DCP and 5 nonexposed male controls participated in the study. The 8-hr average levels of exposure to 1,2-DCP in air and 1,2-DCP in the end-of-shift urine samples were measured with capillary FID-GC. [Results]: The geometric mean (the maximum) concentrations was 7.1 ppm (23.1 ppm) for 1,2-DCP in air, and the level in urine (without correction for urine density) was 77 μg/l (247 μg/l). A regression analysis showed a correlation coefficient of 0.909 (p