DoMosaics: software for domain arrangement visualization and domain-centric analysis of proteins

DoMosaics is an application that unifies protein domain annotation, domain arrangement analysis and visualization in a single tool. It simplifies the analysis of protein families by consolidating disjunct procedures based on often inconvenient command-line applications and complex analysis tools. It...

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Veröffentlicht in:	Bioinformatics 2014-01, Vol.30 (2), p.282-283
Hauptverfasser:	Moore, Andrew D, Held, Andreas, Terrapon, Nicolas, Weiner, 3rd, January, Bornberg-Bauer, Erich
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acyl-tRNA Synthetases - chemistry Amino Acyl-tRNA Synthetases - classification Amino Acyl-tRNA Synthetases - genetics Animals Annotations Bioinformatics Computer Graphics Consolidation Drosophila melanogaster - enzymology Drosophila melanogaster - genetics Evolution Licenses Molecular Sequence Annotation Phylogeny Protein Interaction Domains and Motifs Proteins Proteins - chemistry Proteins - classification Proteins - genetics Software Visualization
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Beschreibung
Zusammenfassung:	DoMosaics is an application that unifies protein domain annotation, domain arrangement analysis and visualization in a single tool. It simplifies the analysis of protein families by consolidating disjunct procedures based on often inconvenient command-line applications and complex analysis tools. It provides a simple user interface with access to domain annotation services such as InterProScan or a local HMMER installation, and can be used to compare, analyze and visualize the evolution of domain architectures. DoMosaics is licensed under theApache License, Version 2.0, and binaries can be freely obtained from www.domosaics.net.
ISSN:	1367-4803 1367-4811 1460-2059
DOI:	10.1093/bioinformatics/btt640