Frequency of sister-chromatid exchange among greenhouse farmers exposed to pesticides

Sister-chromatid exchange (SCE) was measured in peripheral lymphocytes of 104 greenhouse farmers exposed to pesticides and 44 unexposed workers. The results of SCEs are expressed in two variables: (a) mean number of SCEs per chromosome and, (b) proportion of high frequency cells (cells with more tha...

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Veröffentlicht in:	Mutation research 2001-04, Vol.491 (1), p.71-80
Hauptverfasser:	Shaham, Judith, Kaufman, Zalman, Gurvich, Rachel, Levi, Ziva
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Agricultural Workers' Diseases - genetics Biological and medical sciences Cohort Studies Cytogenetic changes farming greenhouses Human Humans Medical sciences Middle Aged Occupational Exposure Pesticides Pesticides - poisoning Pesticides, fertilizers and other agrochemicals toxicology Retrospective Studies Sister Chromatid Exchange Toxicology
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Zusammenfassung:	Sister-chromatid exchange (SCE) was measured in peripheral lymphocytes of 104 greenhouse farmers exposed to pesticides and 44 unexposed workers. The results of SCEs are expressed in two variables: (a) mean number of SCEs per chromosome and, (b) proportion of high frequency cells (cells with more than eight SCEs). A high correlation was found between these two variables. The adjusted means of both SCEs variables were significantly higher among the farmers compared with the unexposed group ( P
ISSN:	1383-5718 0027-5107 1879-3592
DOI:	10.1016/S1383-5718(01)00130-9