Outcomes of Patients at Estimated Low, Intermediate, and High Risk Undergoing Transcatheter Aortic Valve Implantation for Aortic Stenosis

Outcomes of Patients at Estimated Low, Intermediate, and High Risk Undergoing Transcatheter Aortic Valve Implantation for Aortic Stenosis

Intermediate- or low-risk patients with severe aortic stenosis were excluded from earlier transcatheter aortic valve implantation (TAVI) clinical trials; however, they are already being treated by TAVI despite a lack of data regarding the safety and efficacy in these patients. We aimed to assess the...

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Veröffentlicht in:The American journal of cardiology 2015-12, Vol.116 (12), p.1916-1922
Hauptverfasser: Barbash, Israel Moshe, MD, Finkelstein, Ariel, MD, Barsheshet, Alon, MD, Segev, Amit, MD, Steinvil, Arie, MD, Assali, Abid, MD, Ben Gal, Yanai, MD, Vaknin Assa, Hana, MD, Fefer, Paul, MD, Sagie, Alex, MD, Guetta, Victor, MD, Kornowski, Ran, MD
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Aortic Valve Stenosis - mortality
Aortic Valve Stenosis - surgery
Cardiovascular
Female
Follow-Up Studies
Heart attacks
Hospitalization
Hospitals
Humans
Israel - epidemiology
Laboratories
Male
Mortality
Ostomy
Patients
Physicians
Prospective Studies
Pulmonary arteries
Risk Assessment - methods
Risk Factors
Stroke
Studies
Success
Survival Rate - trends
Time Factors
Transcatheter Aortic Valve Replacement
Treatment Outcome
Variables
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Zusammenfassung:Intermediate- or low-risk patients with severe aortic stenosis were excluded from earlier transcatheter aortic valve implantation (TAVI) clinical trials; however, they are already being treated by TAVI despite a lack of data regarding the safety and efficacy in these patients. We aimed to assess the safety and efficacy of TAVI in patients at intermediate or low risk. Patients undergoing TAVI during 2008 to 2014 were included into a shared database (n = 1,327). Procedural outcomes were adjudicated according to Valve Academic Research Consortium 2 definitions. Patients were stratified according to their Society of Thoracic Surgeons (STS) score into 3 groups: high (STS ≥8, n = 223, 17%), intermediate (STS 4 to 8; n = 496, 38%), or low risk (STS
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2015.09.030