A resourceful genome: updating the functional repertoire and evolutionary role of animal mitochondrial DNAs

Highlights • Animal mitochondria are involved in many biological processes besides the production of ATP. • Some animals show non-standard mitochondrial features: unusual protein-coding gene content and/or mtDNA-encoded proteins with extramitochondrial localization and non-oxidative phosphorylation...

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Veröffentlicht in:Trends in genetics 2014-12, Vol.30 (12), p.555-564
Hauptverfasser: Breton, Sophie, Milani, Liliana, Ghiselli, Fabrizio, Guerra, Davide, Stewart, Donald T, Passamonti, Marco
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Sprache:eng
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Zusammenfassung:Highlights • Animal mitochondria are involved in many biological processes besides the production of ATP. • Some animals show non-standard mitochondrial features: unusual protein-coding gene content and/or mtDNA-encoded proteins with extramitochondrial localization and non-oxidative phosphorylation function. • These unusual mitochondrial features are good candidate factors affecting mitochondrial transmission or other aspects of mitochondrial biology, and they may have an important role in lineage-specific adaptations and speciation processes.
ISSN:0168-9525
DOI:10.1016/j.tig.2014.09.002