Integrins LFA-1 and Mac-1 and Cytokines IL-6 and IL-10 in High-Cancer Mice under the Influence of Phytoadaptogen

The expression of leukocyte integrins LFA-1 and Mac-1 and cytokines IL-6 and IL-10 was studied in mice predisposed to spontaneous hepatocarcinomas. The effi cacy of a phytoadaptogen in correcting these parameters was evaluated. The role of adhesive interactions between immune cells and target cells...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bulletin of experimental biology and medicine 2014-06, Vol.157 (2), p.258-260
Hauptverfasser:	Bocharova, O. A., Bocharov, E. V., Karpova, R. V., Il’enko, V. A., Kazeev, I. V., Baryshnikov, A. Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cancer Cell Adhesion - drug effects Cell Biology Hepatoblastoma - blood Hepatoblastoma - metabolism Integrins Interleukin-10 - blood Interleukin-6 - blood Interleukins Internal Medicine Laboratory Medicine Lymphocyte Function-Associated Antigen-1 - metabolism Macrophage-1 Antigen - metabolism Mice Oncology Pathology Plant Extracts - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The expression of leukocyte integrins LFA-1 and Mac-1 and cytokines IL-6 and IL-10 was studied in mice predisposed to spontaneous hepatocarcinomas. The effi cacy of a phytoadaptogen in correcting these parameters was evaluated. The role of adhesive interactions between immune cells and target cells in the recovery of antitumor regulatory mechanisms was estimated.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-014-2539-4