Comparison of genetic variations of the SLCO1B1 , SLCO1B3 , and SLCO2B1 genes among five ethnic groups

Highlights • We compared genetic variation in the SLCO genes from multi-ethnic populations. • Frequencies of the Korean population was similar to East Asian populations. • The distribution of Asian populations was different from African and Caucasian. • We report inter-ethnic differences in the stat...

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Veröffentlicht in:	Environmental toxicology and pharmacology 2015-11, Vol.40 (3), p.692-697
Hauptverfasser:	Namgoong, Suhg, Cheong, Hyun Sub, Kim, Ji On, Kim, Lyoung Hyo, Na, Han Sung, Koh, In Song, Chung, Myeon Woo, Shin, Hyoung Doo
Format:	Artikel
Sprache:	eng
Schlagworte:	African Americans - genetics Asian Americans - genetics Emergency Ethnic diversity Ethnic Groups - genetics European Continental Ancestry Group - genetics Genotype Humans Oligonucleotide Array Sequence Analysis Organic Anion Transporters - genetics Organic Anion Transporters, Sodium-Independent - genetics Organic anion-transporting peptide genes Pharmacogenetics Polymorphism, Single Nucleotide Republic of Korea - ethnology Solute Carrier Organic Anion Transporter Family Member 1b1 Solute Carrier Organic Anion Transporter Family Member 1B3 United States - ethnology
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Zusammenfassung:	Highlights • We compared genetic variation in the SLCO genes from multi-ethnic populations. • Frequencies of the Korean population was similar to East Asian populations. • The distribution of Asian populations was different from African and Caucasian. • We report inter-ethnic differences in the statistical analyses of SLCO families.
ISSN:	1382-6689 1872-7077
DOI:	10.1016/j.etap.2015.08.033