Specificity of JAK-kinase inhibition determines impact on human and murine T-cell function

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Veröffentlicht in:	Leukemia 2016-04, Vol.30 (4), p.991-995
Hauptverfasser:	Perner, F, Schnöder, T M, Ranjan, S, Wolleschak, D, Ebert, C, Pils, M C, Frey, S, Polanetzki, A, Fahldieck, C, Schönborn, U, Schraven, B, Isermann, B, Fischer, T, Heidel, F H
Format:	Artikel
Sprache:	eng
Schlagworte:	42/89 631/80/86 64/60 692/699/1541/1990/2331 82 82/80 96 96/95 Animals Benzamides - pharmacology Cancer Research Care and treatment Cells, Cultured Critical Care Medicine Development and progression Disease Models, Animal Enzyme inhibitors Enzymes Genetic aspects Graft vs Host Disease - drug therapy Graft vs Host Disease - immunology Graft vs Host Disease - metabolism Graft vs Host Disease - pathology Health aspects Hematology Humans Immunosuppression Innovations Intensive Internal Medicine Janus Kinases - antagonists & inhibitors Kinases letter-to-the-editor Lymphocytes T Medicine Medicine & Public Health Methods Mice Mice, Inbred BALB C Molecular targeted therapy Myeloproliferative disorders Myeloproliferative Disorders - drug therapy Myeloproliferative Disorders - immunology Myeloproliferative Disorders - metabolism Myeloproliferative Disorders - pathology Oncology Patient outcomes Phosphotransferases Protein Kinase Inhibitors - pharmacology Pyrimidines - pharmacology Regulation T-Lymphocytes - drug effects T-Lymphocytes - immunology T-Lymphocytes - pathology
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ISSN:	0887-6924 1476-5551
DOI:	10.1038/leu.2015.218