Synthesis of the phorboxazoles—potent, architecturally novel marine natural products

The phorboxazoles have attracted the attention of synthetic chemists around the globe due to their potent biological activity and novel structure. A review of the recent synthetic efforts as well as new phorboxazole analogs is discussed.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of antibiotics 2016-04, Vol.69 (4), p.220-252
Hauptverfasser:	Shultz, Zachary, Leahy, James W
Format:	Artikel
Sprache:	eng
Schlagworte:	639/638/403/933 639/638/549/977 Bacteriology Biological Products - chemical synthesis Biomedical and Life Sciences Bioorganic Chemistry Chemistry Techniques, Synthetic Heterocyclic Compounds, 4 or More Rings - chemical synthesis Life Sciences Medicinal Chemistry Microbiology Organic Chemistry Oxazoles - chemical synthesis review-article
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Beschreibung
Zusammenfassung:	The phorboxazoles have attracted the attention of synthetic chemists around the globe due to their potent biological activity and novel structure. A review of the recent synthetic efforts as well as new phorboxazole analogs is discussed.
ISSN:	0021-8820 1881-1469
DOI:	10.1038/ja.2016.8