Salvage total laryngectomy after external-beam radiotherapy: A 20-year experience

Background The purpose of this study was to present our evaluation of the clinical and functional outcomes after salvage total laryngectomy (STL). Methods We conducted a retrospective review of 218 patients who underwent STL between 1994 and 2014. Results Seventy percent of patients originally had T1 or T2, N0 tumors and 73% had definitive external‐beam radiotherapy (EBRT) alone. A majority utilized tracheoesophageal prosthesis (77%) and were gastrostomy free (80%) at last follow‐up. The 5‐year disease control and overall survival (OS) rates were 65% and 57%, respectively. Patients with a disease‐free interval after initial treatment 5‐year disease‐free interval and 60% for