Two Cases of Fatal Shock after Transfusion of Platelets Contaminated by Staphylococcus aureus: Role of Superantigenic Toxins

We detected Staphylococcus aureus superantigenic toxins in the platelet infusion bags that had been used for 2 patients who subsequently developed transfusion-associated Staphylococcus aureus infection. Both patients, who were immunodeficient, developed manifestations of toxic shock syndrome and sep...

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Veröffentlicht in:	Clinical infectious diseases 2004-11, Vol.39 (10), p.e106-e109
Hauptverfasser:	Perpoint, Thomas, Lina, Gerard, Poyart, Claire, de Barbeyrac, Bertille, Traineau, Richard, Jeanne, Michel, Vandenesch, François, Etienne, Jerome
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antigens, Bacterial - physiology Enterotoxins - physiology Fatal Outcome Humans Male Middle Aged Platelet Transfusion - adverse effects Shock, Septic - etiology Staphylococcus aureus
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Zusammenfassung:	We detected Staphylococcus aureus superantigenic toxins in the platelet infusion bags that had been used for 2 patients who subsequently developed transfusion-associated Staphylococcus aureus infection. Both patients, who were immunodeficient, developed manifestations of toxic shock syndrome and septic shock, and they died soon after the onset of infection.
ISSN:	1058-4838 1537-6591
DOI:	10.1086/425499