Lipoprotein(a) predicts a new onset of chronic kidney disease in people with Type 2 diabetes mellitus

Aims We investigated the association between lipoprotein(a) [Lp(a)] level and new‐onset chronic kidney disease (CKD) in patients with Type 2 diabetes. Methods We conducted a prospective cohort study from March 2003 to December 2004 with a median follow‐up time of 10.1 years. Patients aged 25–75 year...

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Veröffentlicht in:	Diabetic medicine 2016-05, Vol.33 (5), p.639-643
Hauptverfasser:	Yun, J.-S., Ahn, Y.-B., Song, K.-H., Yoo, K.-D., Park, Y.-M., Kim, H.-W., Ko, S.-H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cohort Studies Confidence intervals Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - physiopathology Diabetic Nephropathies - diagnosis Diabetic Nephropathies - epidemiology Female Glomerular Filtration Rate Health risk assessment Hospitals, Teaching Humans Incidence Kidney - physiopathology Kidney diseases Lipoprotein(a) - blood Lipoproteins Longitudinal Studies Male Middle Aged Predictive Value of Tests Proportional Hazards Models Prospective Studies Renal Insufficiency, Chronic - complications Renal Insufficiency, Chronic - diagnosis Renal Insufficiency, Chronic - epidemiology Republic of Korea - epidemiology Risk Factors Up-Regulation
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Zusammenfassung:	Aims We investigated the association between lipoprotein(a) [Lp(a)] level and new‐onset chronic kidney disease (CKD) in patients with Type 2 diabetes. Methods We conducted a prospective cohort study from March 2003 to December 2004 with a median follow‐up time of 10.1 years. Patients aged 25–75 years with Type 2 diabetes and without CKD [estimated glomerular filtration rate (eGFR) ≥ 90 ml/min/1.73 m2) were consecutively enrolled. The eGFR was measured at least twice every year , and new‐onset CKD was defined as a decreased eGFR status of
ISSN:	0742-3071 1464-5491
DOI:	10.1111/dme.12862