A nation-wide epidemiological study on the risk of developing second malignancies in patients with different histological subtypes of nasopharyngeal carcinoma

Highlights • Patients with NPC have a higher risk of SPM regardless of EBV status. • SPM are more prevalent in keratinizing NPC compared to non-keratinizing NPC. • Clinical follow-up of NPC patients, with specific attention on SPM, is justified.

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Bibliographische Detailangaben
Veröffentlicht in:	Oral oncology 2016-05, Vol.56, p.40-46
Hauptverfasser:	Ooft, M.L, van Ipenburg, J, Braunius, W.W, Stegeman, I, Wegner, I, de Bree, R, Overbeek, L.I.H, Koljenović, S, Willems, S.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer registry Carcinoma EBV Epidemiology Epstein Barr Virus Follow-up Hematology, Oncology and Palliative Medicine Histology Humans Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms - classification Nasopharyngeal Neoplasms - pathology Neoplasms, Second Primary - epidemiology Netherlands Otolaryngology Risk Factors Second primary malignancy
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Beschreibung
Zusammenfassung:	Highlights • Patients with NPC have a higher risk of SPM regardless of EBV status. • SPM are more prevalent in keratinizing NPC compared to non-keratinizing NPC. • Clinical follow-up of NPC patients, with specific attention on SPM, is justified.
ISSN:	1368-8375 1879-0593
DOI:	10.1016/j.oraloncology.2016.02.009