Forensic parameters of the Investigator DIPplex kit (Qiagen) in six Mexican populations

Allele frequencies and statistical parameters of forensic efficiency for 30 deletion–insertion polymorphisms (DIPs) were estimated in six Mexican populations. For this purpose, 421 unrelated individuals were analyzed with the Investigator DIPplex kit. The Hardy–Weinberg and linkage equilibrium was demonstrated for this 30-plex system in all six populations. We estimated the combined power of discrimination (PD ≥ 99.999999 %) and combined power of exclusion (PE ≥ 98.632705 %) for this genetic system. A low but significant genetic structure was demonstrated among these six populations by pairwise comparisons and AMOVA ( F ST ≥ 0.7054; p ≤ 0.0007), which allows clustering populations in agreement with geographical criteria: Northwest, Center, and Southeast.