Prevalence and trend of neural tube defects in five counties in Shanxi province of Northern China, 2000 to 2014

Prevalence and trend of neural tube defects in five counties in Shanxi province of Northern China, 2000 to 2014

BACKGROUND The prevalence of neural tube defects (NTDs) in northern China is among the highest in the world. A massive folic acid supplementation program as a specific countermeasure was introduced in 2009. Examining trends in NTD prevalence may provide evidence for future intervention. METHODS Data...

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Veröffentlicht in:Birth defects research. A Clinical and molecular teratology 2016-04, Vol.106 (4), p.267-274
Hauptverfasser: Liu, Jufen, Zhang, Le, Li, Zhiwen, Jin, Lei, Zhang, Yali, Ye, Rongwei, Liu, Jianmeng, Ren, Aiguo
Format: Artikel
Sprache:eng
Schlagworte:
China - epidemiology
Female
folic acid
Folic Acid - administration & dosage
Humans
Male
neural tube defect
Neural Tube Defects - epidemiology
Neural Tube Defects - prevention & control
perinatal
Pregnancy
Prevalence
prevention
Retrospective Studies
Stillbirth - epidemiology
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Zusammenfassung:BACKGROUND The prevalence of neural tube defects (NTDs) in northern China is among the highest in the world. A massive folic acid supplementation program as a specific countermeasure was introduced in 2009. Examining trends in NTD prevalence may provide evidence for future intervention. METHODS Data for 2000 to 2014 in five counties in northern China were obtained through a population‐based birth defects surveillance system. All live births, stillbirths of over 20 gestational weeks, and pregnancy terminations because of NTDs at any gestational age were recorded. The prevalence of NTDs by gestational weeks (
ISSN:1542-0752
1542-0760
DOI:10.1002/bdra.23486