Quercetin is an effective inhibitor of quorum sensing, biofilm formation and virulence factors in Pseudomonas aeruginosa

Quercetin is an effective inhibitor of quorum sensing, biofilm formation and virulence factors in Pseudomonas aeruginosa

Aims The study aimed to perform a systematic investigation of the effects of quercetin on biofilm formation and virulence factors in Pseudomonas aeruginosa. Methods and Results The Ps. aeruginosa strain PAO1 was selected as the test strain. The results indicated that quercetin did not impact the gro...

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Veröffentlicht in:Journal of applied microbiology 2016-04, Vol.120 (4), p.966-974
Hauptverfasser: Ouyang, J., Sun, F., Feng, W., Sun, Y., Qiu, X., Xiong, L., Liu, Y., Chen, Y.
Format: Artikel
Sprache:eng
Schlagworte:
Bacteriology
biofilm
Biofilms
Biofilms - drug effects
Biofilms - growth & development
Microbiology
Pseudomonas aeruginosa
Pseudomonas aeruginosa - drug effects
Pseudomonas aeruginosa - physiology
quercetin
Quercetin - pharmacology
quorum sensing
Quorum Sensing - drug effects
Virology
virulence factors
Virulence Factors - analysis
Virulence Factors - biosynthesis
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Zusammenfassung:Aims The study aimed to perform a systematic investigation of the effects of quercetin on biofilm formation and virulence factors in Pseudomonas aeruginosa. Methods and Results The Ps. aeruginosa strain PAO1 was selected as the test strain. The results indicated that quercetin did not impact the growth of PAO1 as determined by MIC and growth curve analysis. However, this compound significantly inhibited (P 
ISSN:1364-5072
1365-2672
DOI:10.1111/jam.13073