Effect of Erythropoietin on Free Radical Oxidation and Glycoprotein Expression in Platelets under Conditions of Chronic Renal Failure

A short-term open prospective study examined 62 patients at the terminal stage of chronic renal failure. The experimental group received erythropoietin in a total dose of about 40,000 U. The expression of glycoproteins IIb-IIIa, IIb, and Ib was enhanced, the content of LPO products was elevated, and...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2014-05, Vol.157 (1), p.25-27
1. Verfasser:	Osikov, M. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Blood Platelets - drug effects Blood Platelets - metabolism Catalase - blood Cell Biology Chronic kidney failure Drug Administration Schedule Erythropoietin Erythropoietin - therapeutic use Female Free Radicals - antagonists & inhibitors Free Radicals - metabolism Gene Expression - drug effects Humans Internal Medicine Kidney - drug effects Kidney - metabolism Kidney - pathology Kidney Failure, Chronic - drug therapy Kidney Failure, Chronic - genetics Kidney Failure, Chronic - metabolism Kidney Failure, Chronic - pathology Laboratory Medicine Lipid Peroxidation - drug effects Male Middle Aged Oxidation-Reduction Oxidation-reduction reaction Pathology Platelet Glycoprotein GPIb-IX Complex - antagonists & inhibitors Platelet Glycoprotein GPIb-IX Complex - genetics Platelet Glycoprotein GPIb-IX Complex - metabolism Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors Platelet Glycoprotein GPIIb-IIIa Complex - genetics Platelet Glycoprotein GPIIb-IIIa Complex - metabolism Platelet Membrane Glycoprotein IIb - genetics Platelet Membrane Glycoprotein IIb - metabolism Prospective Studies Superoxide Dismutase - blood
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