Effect of Cation Type and Concentration of Nitrates on Neurological Disorders during Experimental Cerebral Ischemia

Experiments were performed on the model of ischemic stroke due to bilateral occlusion of the carotid arteries. Nitrates had various effects on the dynamics of neurological disorders and mortality rate of Wistar rats, which depended on the cation type and concentration.

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Bibliographische Detailangaben
Veröffentlicht in:	Bulletin of experimental biology and medicine 2013-10, Vol.155 (6), p.748-751
Hauptverfasser:	Kuzenkov, V. S., Krushinskii, A. L., Reutov, V. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Brain Ischemia - drug therapy Brain Ischemia - physiopathology Cations Cell Biology Cerebral ischemia Dose-Response Relationship, Drug Drug Evaluation, Preclinical Internal Medicine Laboratory Medicine Magnesium Compounds - administration & dosage Male Motor Activity - drug effects Nervous system diseases Neurological disorders Neuroprotective Agents - administration & dosage Nitrates Nitrates - administration & dosage Pathology Potassium Compounds - administration & dosage Rats Rats, Wistar Recovery of Function - drug effects Treatment Outcome
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Beschreibung
Zusammenfassung:	Experiments were performed on the model of ischemic stroke due to bilateral occlusion of the carotid arteries. Nitrates had various effects on the dynamics of neurological disorders and mortality rate of Wistar rats, which depended on the cation type and concentration.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-013-2243-9