Possible Mechanism of Generation of Nitrite and Non-Thiolate Nitroso Compounds in Blood Plasma during Inflammatory Processes

Generation of nitrite (NO2¯) and non-thiolate nitroso compounds in human blood during leukocyte activation mainly occurred due to destruction of NO donors in the plasma, but not due to intensifi cation of NO synthesis. We proposed a mechanism of production of nitrite and non-thiolate nitroso compoun...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bulletin of experimental biology and medicine 2014-08, Vol.157 (4), p.479-482
Hauptverfasser:	Titov, V. Yu, Boldyrikhin, V. S., Ivanova, A. V., Osipov, A. N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Cell Biology Cells, Cultured Humans Internal Medicine Kinetics Laboratory Medicine Leukocytes - cytology Leukocytes - drug effects Leukocytes - metabolism Nitric Oxide - blood Nitrites - blood Nitroso compounds Nitroso Compounds - blood Pathology Zymosan - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Generation of nitrite (NO2¯) and non-thiolate nitroso compounds in human blood during leukocyte activation mainly occurred due to destruction of NO donors in the plasma, but not due to intensifi cation of NO synthesis. We proposed a mechanism of production of nitrite and non-thiolate nitroso compounds in the blood during infl ammation.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-014-2596-8