The Effects of Phrenic Nerve Degeneration by Axotomy and Crush on the Electrical Activities of Diaphragm Muscles of Rats

The aim of this study was to investigate the effect of axotomy and crush-related degeneration on the electrical activities of diaphragm muscle strips of experimental rats. In the present study, twenty-one male Wistar-albino rats were used and divided into three groups. The animals in the first group...

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Veröffentlicht in:	Cell biochemistry and biophysics 2016-03, Vol.74 (1), p.29-34
Hauptverfasser:	Alkiş, Mehmet Eşref, Kavak, Servet, Sayır, Fuat, Him, Aydin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Biotechnology Cell Biology Diaphragm - innervation Diaphragm - physiology Evoked Potentials, Motor Life Sciences Male Muscles Nerve Degeneration - physiopathology Original Paper Pharmacology/Toxicology Phrenic Nerve - physiology Phrenic Nerve - physiopathology Rats Rats, Wistar
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Beschreibung
Zusammenfassung:	The aim of this study was to investigate the effect of axotomy and crush-related degeneration on the electrical activities of diaphragm muscle strips of experimental rats. In the present study, twenty-one male Wistar-albino rats were used and divided into three groups. The animals in the first group were not crushed or axotomized and served as controls. Phrenic nerves of the rats in the second and third groups were crushed or axotomized in the diaphragm muscle. Resting membrane potential (RMP) was decreased significantly in both crush and axotomy of diaphragm muscle strips of experimental rats ( p
ISSN:	1085-9195 1559-0283
DOI:	10.1007/s12013-015-0708-3