Effect of subconjunctival glucose on retinal ganglion cell survival in experimental retinal ischaemia and contrast sensitivity in human glaucoma

Purpose This study aims to evaluate the effect of subconjunctival glucose on the retinal ganglion cells (RGCs) in experimental retinal ischaemia and contrast sensitivity in humans with primary open‐angle glaucoma (POAG). Methods First, we measured the intravitreal concentration of glucose at various...

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Veröffentlicht in:	Clinical & experimental ophthalmology 2016-01, Vol.44 (1), p.24-32
Hauptverfasser:	Shibeeb, O'Sam, Chidlow, Glyn, Han, Guoge, Wood, John PM, Casson, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animals Apoptosis Axons - physiology bioenergetic neuroprotection Cell Count Cell Survival - drug effects Conjunctiva - drug effects Contrast Sensitivity - physiology Cross-Over Studies Disease Models, Animal Double-Blind Method Female glaucoma Glaucoma, Open-Angle - drug therapy Glaucoma, Open-Angle - physiopathology Glucose - administration & dosage Humans Injections, Intraocular ischaemia Ischemia - metabolism Ischemia - prevention & control Male neurorecovery Pilot Projects Rats Rats, Sprague-Dawley retinal ganglion cell Retinal Ganglion Cells - cytology Retinal Ganglion Cells - physiology Retinal Vessels - drug effects Sweetening Agents - administration & dosage Visual Fields - physiology Vitreous Body - metabolism
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