Safety and efficacy of ledipasvir/sofosbuvir for the treatment of genotype 1 hepatitis C in subjects aged 65 years or older

Elderly subjects have been historically underrepresented in clinical trials involving antiviral hepatitis C therapies. The aim of this analysis was to retrospectively evaluate the safety and efficacy of ledipasvir/sofosbuvir (LDV/SOF) by age groups of

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2016-04, Vol.63 (4), p.1112-1119
Hauptverfasser:	Saab, Sammy, Park, Sarah H., Mizokami, Masashi, Omata, Masao, Mangia, Alessandra, Eggleton, Ed, Zhu, Yanni, Knox, Steven J., Pang, Phil, Subramanian, Mani, Kowdley, Kris, Afdhal, Nezam H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age Factors Aged Aged, 80 and over Antiviral Agents - administration & dosage Benzimidazoles - administration & dosage Clinical trials Clinical Trials, Phase III as Topic Cohort Studies Confidence Intervals Dose-Response Relationship, Drug Drug Administration Schedule Drug Therapy, Combination Fatigue Female Fluorenes - administration & dosage Follow-Up Studies Genotype Genotype & phenotype Geriatrics Headache Hepatitis Hepatitis C Hepatitis C virus Hepatitis C, Chronic - diagnosis Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - genetics Hepatology Humans Interferon Liver Cirrhosis - prevention & control Liver Cirrhosis - virology Male Patient Safety - statistics & numerical data Randomized Controlled Trials as Topic Retrospective Studies Ribavirin Ribavirin - administration & dosage Risk Assessment Sex Factors Sofosbuvir - administration & dosage Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Elderly subjects have been historically underrepresented in clinical trials involving antiviral hepatitis C therapies. The aim of this analysis was to retrospectively evaluate the safety and efficacy of ledipasvir/sofosbuvir (LDV/SOF) by age groups of
ISSN:	0270-9139 1527-3350
DOI:	10.1002/hep.28425