A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea

An HIV-negative man with pharyngeal gonorrhea had a positive test-of-cure (nucleic acid amplification test) result 7 days after treatment with ceftriaxone/azithromycin. Neisseria gonorrhoeae Multi-Antigen Sequencing Type 1407 and mosaic pen A (XXXIV) gene were identified in the test-of-cure specimen...

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Veröffentlicht in:	Sexually transmitted diseases 2016-04, Vol.43 (4), p.258-259
Hauptverfasser:	Levy, Vivian, Pandori, Mark, Berrada, Zenda L., Relucio, Karen I., Lopez, Teresa P., Samuel, Michael C., Park, Ina U.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - therapeutic use Antibiotics Asymptomatic Diseases Azithromycin Azithromycin - therapeutic use Case Report Ceftriaxone Ceftriaxone - therapeutic use Cure Gene sequencing Gonorrhea Gonorrhea - drug therapy HIV Human immunodeficiency virus Humans Injections, Intramuscular Male Men Neisseria gonorrhoeae Neisseria gonorrhoeae - genetics Neisseria gonorrhoeae - immunology Nucleic Acid Amplification Techniques Nucleic acids Pharynx Pharynx - microbiology Sexually transmitted diseases Sexually Transmitted Diseases - drug therapy STD Treatment Outcome Young Adult
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Beschreibung
Zusammenfassung:	An HIV-negative man with pharyngeal gonorrhea had a positive test-of-cure (nucleic acid amplification test) result 7 days after treatment with ceftriaxone/azithromycin. Neisseria gonorrhoeae Multi-Antigen Sequencing Type 1407 and mosaic pen A (XXXIV) gene were identified in the test-of-cure specimen, and culture was negative. Retreatment with ceftriaxone500mgintramuscularlyplusazithromycin2gorallyyieldedanegative test-of-cure result.
ISSN:	0148-5717 1537-4521
DOI:	10.1097/OLQ.0000000000000430