Free Radical Oxidation in Rat Myocardium after Maximum Permissible Hepatic Resection

Free radical oxidation in rat myocardial homogenate was studied by chemiluminescent assay during the early terms after maximum permissible liver resection. During this period, activation of free radical oxidation was biphasic. The critical terms characterized by dramatic intensification of free radi...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2016-03, Vol.160 (5), p.625-627
Hauptverfasser:	Ermolaev, P. A., Khramykh, T. P., Barskaya, L. O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cell Biology Free Radicals - metabolism Hepatectomy - adverse effects Internal Medicine Laboratory Medicine Liver Liver - surgery Male Myocardial Ischemia - physiopathology Myocardium - metabolism Oxidation-Reduction Oxidation-reduction reactions Pathology Rats Stress, Physiological - physiology Surgery
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Zusammenfassung:	Free radical oxidation in rat myocardial homogenate was studied by chemiluminescent assay during the early terms after maximum permissible liver resection. During this period, activation of free radical oxidation was biphasic. The critical terms characterized by dramatic intensification of free radical oxidation in the myocardium are the first hour and the first day after surgery. The period from 3 to 12 h after surgery, in which the indices of chemiluminescence decrease, can be tentatively termed as the period of “putative wellbeing”. Normalization of the free radical oxidation processes in the myocardium occurred by day 7 after surgery.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-016-3233-5