The effect of quantitative and qualitative antiepileptic drug changes on cognitive recovery after epilepsy surgery

Highlights • Epilepsy surgery can cause cognitive decline and improvement as well. • Neuropsychological outcome depends on surgery, seizure control, and drug treatment. • Quantitative drug load reduction positively affects executive functions. • Qualitative drug change positively affects memory and...

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Veröffentlicht in:	Seizure (London, England) England), 2016-03, Vol.36, p.63-69
Hauptverfasser:	Helmstaedter, Christoph, PhD, Elger, Christian Erich, MD, Witt, Juri-Alexander, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Affect - drug effects Analysis of Variance Anticonvulsants - therapeutic use Antiepileptic drugs Cognition Disorders - drug therapy Cognition Disorders - etiology Epilepsy - drug therapy Epilepsy - surgery Executive function Executive Function - drug effects Female Humans Male Memory Memory - drug effects Middle Aged Mood Neurology Neuropsychological Tests Neurosurgical Procedures - adverse effects Postoperative Complications - drug therapy Postoperative Complications - physiopathology Retrospective Studies Treatment Outcome
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Beschreibung
Zusammenfassung:	Highlights • Epilepsy surgery can cause cognitive decline and improvement as well. • Neuropsychological outcome depends on surgery, seizure control, and drug treatment. • Quantitative drug load reduction positively affects executive functions. • Qualitative drug change positively affects memory and mood.
ISSN:	1059-1311 1532-2688
DOI:	10.1016/j.seizure.2016.02.001