The role of PET scan in monitoring the progression of fibrosing mediastinitis
Abstract We present the case of a 31-year-old man who presented with acute chest pain. Computed tomography scan showed a mediastinal mass engulfing right main-stem bronchus and another mass surrounding descending aorta. Positron emission tomography (PET) scan showed high mass metabolic activity. His...
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Veröffentlicht in: | Clinical imaging 2016-01, Vol.40 (1), p.177-179 |
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description | Abstract We present the case of a 31-year-old man who presented with acute chest pain. Computed tomography scan showed a mediastinal mass engulfing right main-stem bronchus and another mass surrounding descending aorta. Positron emission tomography (PET) scan showed high mass metabolic activity. Histopathological evaluation revealed fibroinflammatory scarring. He was diagnosed with idiopathic fibrosing mediastinitis, started on prednisone and tamoxifen treatment, and monitored with serial PET scans. Nine months after treatment initiation, paraaortic abnormality had resolved and mediastinal mass had regressed. |
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Computed tomography scan showed a mediastinal mass engulfing right main-stem bronchus and another mass surrounding descending aorta. Positron emission tomography (PET) scan showed high mass metabolic activity. Histopathological evaluation revealed fibroinflammatory scarring. He was diagnosed with idiopathic fibrosing mediastinitis, started on prednisone and tamoxifen treatment, and monitored with serial PET scans. Nine months after treatment initiation, paraaortic abnormality had resolved and mediastinal mass had regressed.</description><identifier>ISSN: 0899-7071</identifier><identifier>EISSN: 1873-4499</identifier><identifier>DOI: 10.1016/j.clinimag.2015.07.030</identifier><identifier>PMID: 26414539</identifier><identifier>CODEN: CLIMEB</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Abnormalities ; Adult ; Anti-Inflammatory Agents - therapeutic use ; Antigens ; Biopsy ; Coronary vessels ; Diagnosis, Differential ; Disease ; Disease Progression ; Drug dosages ; Family medical history ; Fibrosis ; Humans ; Infections ; Laboratories ; Male ; Mediastinitis ; Mediastinitis - diagnostic imaging ; Mediastinitis - drug therapy ; Mediastinum - diagnostic imaging ; Medical imaging ; Metabolism ; Monitoring ; Pain ; Patients ; PET scan ; Positron emission ; Positron-Emission Tomography ; Prednisone - therapeutic use ; Progressions ; Radiology ; Scars ; Sclerosis - diagnostic imaging ; Sclerosis - drug therapy ; Selective Estrogen Receptor Modulators - therapeutic use ; Serials ; Steroids ; Tamoxifen ; Tamoxifen - therapeutic use ; Tomography</subject><ispartof>Clinical imaging, 2016-01, Vol.40 (1), p.177-179</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c517t-41e941f10ff16fd89359390df9a7c41d587fe032d2c0bea830f4e95c350e86593</citedby><cites>FETCH-LOGICAL-c517t-41e941f10ff16fd89359390df9a7c41d587fe032d2c0bea830f4e95c350e86593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.clinimag.2015.07.030$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26414539$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kaya, Hatice</creatorcontrib><creatorcontrib>Rider, Katherine</creatorcontrib><creatorcontrib>Cho, Alexander H</creatorcontrib><creatorcontrib>Schwartz, Arnold</creatorcontrib><creatorcontrib>Alrehaili, Ghadah</creatorcontrib><creatorcontrib>Ahari, Jalil</creatorcontrib><title>The role of PET scan in monitoring the progression of fibrosing mediastinitis</title><title>Clinical imaging</title><addtitle>Clin Imaging</addtitle><description>Abstract We present the case of a 31-year-old man who presented with acute chest pain. Computed tomography scan showed a mediastinal mass engulfing right main-stem bronchus and another mass surrounding descending aorta. Positron emission tomography (PET) scan showed high mass metabolic activity. Histopathological evaluation revealed fibroinflammatory scarring. He was diagnosed with idiopathic fibrosing mediastinitis, started on prednisone and tamoxifen treatment, and monitored with serial PET scans. Nine months after treatment initiation, paraaortic abnormality had resolved and mediastinal mass had regressed.</description><subject>Abnormalities</subject><subject>Adult</subject><subject>Anti-Inflammatory Agents - therapeutic use</subject><subject>Antigens</subject><subject>Biopsy</subject><subject>Coronary vessels</subject><subject>Diagnosis, Differential</subject><subject>Disease</subject><subject>Disease Progression</subject><subject>Drug dosages</subject><subject>Family medical history</subject><subject>Fibrosis</subject><subject>Humans</subject><subject>Infections</subject><subject>Laboratories</subject><subject>Male</subject><subject>Mediastinitis</subject><subject>Mediastinitis - diagnostic imaging</subject><subject>Mediastinitis - drug therapy</subject><subject>Mediastinum - diagnostic imaging</subject><subject>Medical imaging</subject><subject>Metabolism</subject><subject>Monitoring</subject><subject>Pain</subject><subject>Patients</subject><subject>PET scan</subject><subject>Positron emission</subject><subject>Positron-Emission Tomography</subject><subject>Prednisone - therapeutic use</subject><subject>Progressions</subject><subject>Radiology</subject><subject>Scars</subject><subject>Sclerosis - diagnostic imaging</subject><subject>Sclerosis - drug therapy</subject><subject>Selective Estrogen Receptor Modulators - therapeutic use</subject><subject>Serials</subject><subject>Steroids</subject><subject>Tamoxifen</subject><subject>Tamoxifen - therapeutic use</subject><subject>Tomography</subject><issn>0899-7071</issn><issn>1873-4499</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkk1v1DAQhi0EokvhL1SRuHBJmInt2L4gUFU-pCKQWM5W1hkvXrJxsbNI_fc43RakXujJBz_zemYeM3aG0CBg93rXuDFMYd9vmxZQNqAa4PCIrVArXgthzGO2Am1MrUDhCXuW8w5KoRHqKTtpO4FCcrNin9c_qEpxpCr66uvFusqun6owVfs4hTmmMG2ruSBXKW4T5RzitJA-bFLMy-WehtDnufQyh_ycPfH9mOnF7XnKvr-_WJ9_rC-_fPh0_u6ydhLVXAskI9AjeI-dH7Th0nADgze9cgIHqZUn4O3QOthQrzl4QUY6LoF0V9hT9uqYW9r6daA8233IjsaxnygeskWlNIDWBh-ASi6kUqp9CIpCS-y6gr68h-7iIU1l5pvAtjQpVaG6I-XKsnIib69SUZauLYJdNNqdvdNoF40WlC0aS-HZbfxhUxb8t-zOWwHeHgEqW_4dKNnsAk2uyEjkZjvE8P833tyLuMFcP_6ka8r_5rG5tWC_LZ9p-UsoAVoExf8AghrEBg</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Kaya, Hatice</creator><creator>Rider, Katherine</creator><creator>Cho, Alexander H</creator><creator>Schwartz, Arnold</creator><creator>Alrehaili, Ghadah</creator><creator>Ahari, Jalil</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope><scope>7QO</scope><scope>7U5</scope><scope>L7M</scope></search><sort><creationdate>20160101</creationdate><title>The role of PET scan in monitoring the progression of fibrosing mediastinitis</title><author>Kaya, Hatice ; Rider, Katherine ; Cho, Alexander H ; Schwartz, Arnold ; Alrehaili, Ghadah ; Ahari, Jalil</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c517t-41e941f10ff16fd89359390df9a7c41d587fe032d2c0bea830f4e95c350e86593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Abnormalities</topic><topic>Adult</topic><topic>Anti-Inflammatory Agents - therapeutic use</topic><topic>Antigens</topic><topic>Biopsy</topic><topic>Coronary vessels</topic><topic>Diagnosis, Differential</topic><topic>Disease</topic><topic>Disease Progression</topic><topic>Drug dosages</topic><topic>Family medical history</topic><topic>Fibrosis</topic><topic>Humans</topic><topic>Infections</topic><topic>Laboratories</topic><topic>Male</topic><topic>Mediastinitis</topic><topic>Mediastinitis - diagnostic imaging</topic><topic>Mediastinitis - drug therapy</topic><topic>Mediastinum - diagnostic imaging</topic><topic>Medical imaging</topic><topic>Metabolism</topic><topic>Monitoring</topic><topic>Pain</topic><topic>Patients</topic><topic>PET scan</topic><topic>Positron emission</topic><topic>Positron-Emission Tomography</topic><topic>Prednisone - therapeutic use</topic><topic>Progressions</topic><topic>Radiology</topic><topic>Scars</topic><topic>Sclerosis - diagnostic imaging</topic><topic>Sclerosis - drug therapy</topic><topic>Selective Estrogen Receptor Modulators - therapeutic use</topic><topic>Serials</topic><topic>Steroids</topic><topic>Tamoxifen</topic><topic>Tamoxifen - therapeutic use</topic><topic>Tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kaya, Hatice</creatorcontrib><creatorcontrib>Rider, Katherine</creatorcontrib><creatorcontrib>Cho, Alexander H</creatorcontrib><creatorcontrib>Schwartz, Arnold</creatorcontrib><creatorcontrib>Alrehaili, Ghadah</creatorcontrib><creatorcontrib>Ahari, Jalil</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Clinical imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kaya, Hatice</au><au>Rider, Katherine</au><au>Cho, Alexander H</au><au>Schwartz, Arnold</au><au>Alrehaili, Ghadah</au><au>Ahari, Jalil</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The role of PET scan in monitoring the progression of fibrosing mediastinitis</atitle><jtitle>Clinical imaging</jtitle><addtitle>Clin Imaging</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>40</volume><issue>1</issue><spage>177</spage><epage>179</epage><pages>177-179</pages><issn>0899-7071</issn><eissn>1873-4499</eissn><coden>CLIMEB</coden><abstract>Abstract We present the case of a 31-year-old man who presented with acute chest pain. Computed tomography scan showed a mediastinal mass engulfing right main-stem bronchus and another mass surrounding descending aorta. Positron emission tomography (PET) scan showed high mass metabolic activity. Histopathological evaluation revealed fibroinflammatory scarring. He was diagnosed with idiopathic fibrosing mediastinitis, started on prednisone and tamoxifen treatment, and monitored with serial PET scans. Nine months after treatment initiation, paraaortic abnormality had resolved and mediastinal mass had regressed.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26414539</pmid><doi>10.1016/j.clinimag.2015.07.030</doi><tpages>3</tpages></addata></record> |
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subjects | Abnormalities Adult Anti-Inflammatory Agents - therapeutic use Antigens Biopsy Coronary vessels Diagnosis, Differential Disease Disease Progression Drug dosages Family medical history Fibrosis Humans Infections Laboratories Male Mediastinitis Mediastinitis - diagnostic imaging Mediastinitis - drug therapy Mediastinum - diagnostic imaging Medical imaging Metabolism Monitoring Pain Patients PET scan Positron emission Positron-Emission Tomography Prednisone - therapeutic use Progressions Radiology Scars Sclerosis - diagnostic imaging Sclerosis - drug therapy Selective Estrogen Receptor Modulators - therapeutic use Serials Steroids Tamoxifen Tamoxifen - therapeutic use Tomography |
title | The role of PET scan in monitoring the progression of fibrosing mediastinitis |
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