The role of PET scan in monitoring the progression of fibrosing mediastinitis

Abstract We present the case of a 31-year-old man who presented with acute chest pain. Computed tomography scan showed a mediastinal mass engulfing right main-stem bronchus and another mass surrounding descending aorta. Positron emission tomography (PET) scan showed high mass metabolic activity. His...

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Veröffentlicht in:	Clinical imaging 2016-01, Vol.40 (1), p.177-179
Hauptverfasser:	Kaya, Hatice, Rider, Katherine, Cho, Alexander H, Schwartz, Arnold, Alrehaili, Ghadah, Ahari, Jalil
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Adult Anti-Inflammatory Agents - therapeutic use Antigens Biopsy Coronary vessels Diagnosis, Differential Disease Disease Progression Drug dosages Family medical history Fibrosis Humans Infections Laboratories Male Mediastinitis Mediastinitis - diagnostic imaging Mediastinitis - drug therapy Mediastinum - diagnostic imaging Medical imaging Metabolism Monitoring Pain Patients PET scan Positron emission Positron-Emission Tomography Prednisone - therapeutic use Progressions Radiology Scars Sclerosis - diagnostic imaging Sclerosis - drug therapy Selective Estrogen Receptor Modulators - therapeutic use Serials Steroids Tamoxifen Tamoxifen - therapeutic use Tomography
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Zusammenfassung:	Abstract We present the case of a 31-year-old man who presented with acute chest pain. Computed tomography scan showed a mediastinal mass engulfing right main-stem bronchus and another mass surrounding descending aorta. Positron emission tomography (PET) scan showed high mass metabolic activity. Histopathological evaluation revealed fibroinflammatory scarring. He was diagnosed with idiopathic fibrosing mediastinitis, started on prednisone and tamoxifen treatment, and monitored with serial PET scans. Nine months after treatment initiation, paraaortic abnormality had resolved and mediastinal mass had regressed.
ISSN:	0899-7071 1873-4499
DOI:	10.1016/j.clinimag.2015.07.030