Changes in intrafollicular concentrations of free IGF-1, activin A, inhibin A, VEGF, estradiol, and prolactin before ovulation in mares

Changes in intrafollicular growth factors and hormones were evaluated in vivo in postdeviation and impending ovulation follicles. Mares (n = 30) were randomly assigned to five experimental groups based on target diameters of 25, 30, 35, 40 mm, and impending signs of ovulation. Furthermore, data belo...

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Veröffentlicht in:	Theriogenology 2016-05, Vol.85 (8), p.1491-1498
Hauptverfasser:	Bashir, S.T., Ishak, G.M., Gastal, M.O., Roser, J.F., Gastal, E.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Activins - metabolism Animals Estradiol - metabolism Female Follicle deviation Follicular Fluid - metabolism Hormone Horses - metabolism Impending ovulation Inhibins - metabolism Insulin-Like Growth Factor I - metabolism Intercellular Signaling Peptides and Proteins - metabolism Intrafollicular growth factor Mare Ovarian Follicle - growth & development Ovarian Follicle - metabolism Ovulation - metabolism Prolactin - metabolism Random Allocation Vascular Endothelial Growth Factor A - metabolism
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Zusammenfassung:	Changes in intrafollicular growth factors and hormones were evaluated in vivo in postdeviation and impending ovulation follicles. Mares (n = 30) were randomly assigned to five experimental groups based on target diameters of 25, 30, 35, 40 mm, and impending signs of ovulation. Furthermore, data belonging to two or more proximal diameter groups that were not different were combined and regrouped for each factor separately. Follicular fluid-free insulin-like growth factor 1 was highest (P 0.05) among groups. Additionally, follicular fluid activin A tended (P
ISSN:	0093-691X 1879-3231
DOI:	10.1016/j.theriogenology.2016.01.013