PCR study of the human herpes virus type 6 and other viruses of the herpes group in eye diseases

To study the role of the HHV-6 type in the development of eye diseases PCR tests of blood (152), cornea biopsies (61), and intraocular fluids (11) for HHV-6 and other viruses of the herpes group (HSV type 1 and 2, CMV, EBV) were conducted. It was found that the HHV-6, along with other representative...

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Veröffentlicht in:	Voprosy virusologiĭ 2015, Vol.60 (6), p.45-48
Hauptverfasser:	Slepowa, O S, Svetlova, E V, Kovaleva, L A, Makarov, P V, Kugusheva, A E, Denisova, E V, Vahova, E S, Zaharova, G Yu, Kondrat'eva, Yu A, Andryushin, A E, Demkin, V V
Format:	Artikel
Sprache:	rus
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anterior Chamber - pathology Anterior Chamber - virology Aqueous Humor - virology Child Child, Preschool Cornea - pathology Cornea - virology Cytomegalovirus - genetics Cytomegalovirus - isolation & purification DNA, Viral - genetics Eye Diseases - diagnosis Eye Diseases - pathology Eye Diseases - virology Female Herpesviridae Infections - diagnosis Herpesviridae Infections - pathology Herpesviridae Infections - virology Herpesvirus 1, Human - genetics Herpesvirus 1, Human - isolation & purification Herpesvirus 2, Human - genetics Herpesvirus 2, Human - isolation & purification Herpesvirus 4, Human - genetics Herpesvirus 4, Human - isolation & purification Herpesvirus 6, Human - genetics Herpesvirus 6, Human - isolation & purification Humans Male Middle Aged Polymerase Chain Reaction
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Zusammenfassung:	To study the role of the HHV-6 type in the development of eye diseases PCR tests of blood (152), cornea biopsies (61), and intraocular fluids (11) for HHV-6 and other viruses of the herpes group (HSV type 1 and 2, CMV, EBV) were conducted. It was found that the HHV-6, along with other representatives of the Herpesviridae, can be detected in patients with different clinical forms of ophthalmopathology (174 patients were surveyed). Viral DNA was detected in blood, cornea, and in the anterior chamber fluid. The obtained data allow that the HHV-6 to be suggested as a possible cause of the ophthalmic herpes along with the other viruses of this group. It makes finding the virus DNA an essential step towards setting the etiologic diagnosis of the ophthalmological patients.
ISSN:	0507-4088