HEPES is not suitable for fluorescence detection of HClO: a novel probe for HClO in absolute PBS

HEPES is not suitable for fluorescence detection of HClO because it can be oxidized by HClO. A novel probe for HClO, which can selectively and sensitively detect HClO in absolute PBS, was developed on the basis of an oxidation reaction with an azo moiety. Furthermore, it works well in live mouse ima...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2016-04, Vol.52 (28), p.564-566
Hauptverfasser: Xing, Panfei, Gao, Kuo, Wang, Beng, Gao, Jian, Yan, Hui, Wen, Jia, Li, Weisi, Xu, Yongqian, Li, Hongjuan, Chen, Jianxin, Wang, Wei, Sun, Shiguo
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container_end_page 566
container_issue 28
container_start_page 564
container_title Chemical communications (Cambridge, England)
container_volume 52
creator Xing, Panfei
Gao, Kuo
Wang, Beng
Gao, Jian
Yan, Hui
Wen, Jia
Li, Weisi
Xu, Yongqian
Li, Hongjuan
Chen, Jianxin
Wang, Wei
Sun, Shiguo
description HEPES is not suitable for fluorescence detection of HClO because it can be oxidized by HClO. A novel probe for HClO, which can selectively and sensitively detect HClO in absolute PBS, was developed on the basis of an oxidation reaction with an azo moiety. Furthermore, it works well in live mouse imaging. HEPES is not suitable for fluorescence detection of HClO. A novel probe for HClO was developed in absolute PBS.
doi_str_mv 10.1039/c6cc00880a
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source MEDLINE; Alma/SFX Local Collection; Royal Society of Chemistry E-Journals
subjects Animals
Azo
Buffers
Fluorescence
Fluorescent Dyes - analysis
Fluorescent Dyes - chemistry
HEPES - chemistry
Hypochlorous Acid - analysis
Imaging
Mice
Oxidation
Phosphates - chemistry
title HEPES is not suitable for fluorescence detection of HClO: a novel probe for HClO in absolute PBS
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